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Eighteen children in every hour were infected with HIV last year.
UNICEF said that this was a sign of scant progress in protecting the world’s young from the deadly AIDS-causing virus.
At the current rate of infection, there will be 3.5 million new cases of HIV among adolescents by 2030, according to projections in the 2017 UNICEF Statistical Update on Children and AIDS.
Around the world, nearly 37 million people – the equivalent of the population of Canada – were living with HIV last year, according to UNICEF.
Among these, 2.1 million adolescents had HIV, a 30 per cent increase from 2005, while 55,000 adolescents aged 10 to 19 and 120,000 children younger than 14 died from AIDS-related causes.
Infected children, younger than 4 years old, faced the highest risk of AIDS-related deaths compared with other age groups.
“The AIDS epidemic is not over; it remains a threat to the lives of children and young people,” said Dr Chewe Luo, the Chief of HIV for UNICEF, in a statement accompanying the report.
“It is unacceptable that we continue to see so many children dying from AIDS and so little progress made to protect adolescents from new HIV infections.”
UNICEF said nearly all the adolescent deaths were in sub-Saharan Africa and, worldwide, more adolescent girls than boys are infected.
The testing and treatment of babies is also lagging with fewer than half of HIV-exposed infants getting tested in their first two months of life.
UNICEF said some progress had been made in preventing mother-to-child transmission with about two million new infections averted since 2000, it said, but that progress was slowing.
UNICEF called for an array of actions, including getting treatment to all infected children, making intervention for adolescent girls in sub-Saharan Africa a priority, while also introducing HIV self-testing and better data collection.